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First, concerning thromboembolism risk, transdermal estradiol avoids the "first-pass" effect, thus minimizing the induction of clotting factors by the liver.
We agree with Dr Collignon that convincing data indicate that use of antimicrobial agents that are of human importance among food animals has an adverse human health impact and that the time has come to find alternatives that promote food-animal health while minimizing the induction of antimicrobial resistance.
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A major challenge in developing the checkpoint-based therapy for autoimmune diseases is identifying pathways that will minimize the induction of adverse global immune suppression that impairs the host protective immunity against cancer and microbial pathogens.
It was proved that superficially attacking the synthetic jarosite with arsenic in HNO3 (a way to create defects or to remove submicron films) minimizes the induction period.
We found that a 50 ng/ml dose of CyaA was optimal to maximize the induction of intracellular cAMP and to minimize the induction of apoptosis (data not shown).
The spider mite Tetranychus evansi, for example, is able to minimize the induction of direct (proteinase inhibitor accumulation) and indirect (volatile emission) defenses in tomato plants [ 88].
With respect to the excess of signaling pathways downstream of certain kinases, selective tyrosine kinase inhibitors have some advantages in order to minimize the induction of toxicities.
Statistical analysis showed no diameter differences between challenges or at different time-points, minimizing the possibility of induction of tolerance during the in vivo protocol.
This procedure should help to minimize the artificial induction of stress-responsive genes during the experiments.
This paper, therefore, presents a method of finding an optimal value of the capacitor under voltage constraint for maximizing the output power of an induction heater, while minimizing the power loss of the capacitor at the same time.
This may be due to the high basal expression displayed by the native osmotin promoter in the absence of ERF effectors, which likely minimizes the induction effect observed in the presence of ERFs (Additional file 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com