Sentence examples for minimize the binding from inspiring English sources

Mutations that minimize the binding energy with the desired ligand are identified.

Furthermore, a specific conformation of the bound β2GPI as a single molecule or of a β2GPI layer could minimize the binding of aD4 5 and, thus, bring about the high specificity of aPG analysis.

To minimize the binding of NPS to the plastic surfaces and to reduce peptidase activity, bovine serum albumin (0.2%) and bacitracin (0.03%) were included in the perfusion medium.

In the second step, POSWOI was removed from Avicel to minimize the binding competition of the substrate, and the pretreated Avicel was subjected to hydrolysis by cellulases alone.

It is important to emphasize that the solutions of the MIP formulation not only extract an accurate interaction code but also predict the interaction submodels that minimize the binding free energy of each complex.

Another theory attributes TpA avoidance in coding regions to its presence in noncoding regulatory motifs such as TATA box and transcription termination regions, thus minimizing the binding of transcription factors to the false initiation sites generated and avoiding spurious transcription [53].

Quartz glass was functionalized with PEG-biotin and PEG (1∶40 in a mass ratio, Laysan Bio), while cover glass was functionalized only with PEG to minimize the nonspecific binding of the DNA substrates or proteins [28].

It is demonstrated that polyacrylic acid coatings are an excellent choice to minimize the nonspecific binding of the bases.

In order to provide low biofouling properties and minimize the nonspecific binding of proteins, vacant regions of the electrode were covered by a monolayer of PEG-silane copolymer.

We performed protein precipitation before the on-chip SPE to minimize the nonspecific binding of the mostly hydrophobic PFCs to plasma proteins, thereby maximizing their extraction efficiency.

Fig. 1 a Schematic diagram of the ONW array geometry on a gold electrode designed to minimize the unwanted, nonspecific binding or aggregation of biomaterials.