Sentence examples for minimal response rate from inspiring English sources

We aimed for a minimal response rate of 60%.

In surveys there is no scientific agreement on what is considered to be the minimal response rate, but in general a response rate of 60% is considered to be the threshold for an acceptable response rate [ 24].

According to Simon's minimax two-stage phase II study design, the treatment programme was designed for a minimal response rate of 15% and to provide a significance level of 0.10 with a statistical power of 80% in assessing the activity of the regimen according to a 35% response rate.

Importantly, at the same prescribed dose, slow NAT2 acetylators were believed to be underdosed as reflected by minimal response rate and lack of grade 3 myelosuppression while rapid acetylators had greater haematologic toxicity attributed to slower clearance of the parent amonafide (Ratain et al, 1991, 1993).

In the case of itraconazole (9), minimal response rates were observed in cases of CL resulting from L. major and in MCL originating from L. braziliensis.

However, the minimal response rates along with the disappointing PFS results obtained in the present study did not support this further step of clinical development.

This is achieved by setting up the threshold as the minimal effective response rate.

Overall, an objective response (complete or partial response) and more than minimal response (MR) rates were documented in 53.5% and 69.0% of patients, respectively.

In this case, initial treatment could be tailored to the individual and we could aim at shortening the time to onset of effective treatment, improving the cost-benefit and risk-benefit ratios of these agents, and eventually achieving 100% response rate with minimal toxicity.

Clinical evidence indicates that there are minimal differences in efficacy (objective response rate and overall survival) between the various platinum-based doublet regimens in the treatment of advanced NSCLC [ 11, 12], and that the addition of a third cytotoxic agent increases toxicity but does not prolong survival [ 13].

The impact of conventional systemic therapy for metastatic melanoma is minimal, with best response rates for conventional therapy nearing only 30% and cure rates well below 10%.