Sentence examples for minimal mutation rate from inspiring English sources

This vast mutation engine, even if one assumes a minimal mutation rate, generates the equivalent of hundreds of new complete human genomes per day.

Since there is no discontinuous transition from sites with zero mutation rate to a high mutation rate, there is always a class of sites with a minimal mutation rate fully conforming to the infinite sites model, and this class of sites is precisely the one most valuable for phylogenetic inference.

For phage populations with minimal genetic load, engineering mutation rate increases beyond the mutation selection balance optimum may provide even greater protection against emergent bacterial types, but only with very weak selective coefficients for de novo deleterious mutations (below ∼0.01).

The minimal model dynamics depends on mutation rate, sequence length, strength and flip rate of selection, and population size.

Although the KRAS mutation rate was minimal in the conventional adenoma cohorts, similarly low rates, particularly for TAs, have been previously found [ 20, 30], and wide variations of KRAS mutation rates in adenomas have been reported [ 31- 33].

For the fitness landscape with a peak mesa profile, the two-dimensional phase diagram in the mesa fitness and the mutation rate can be computed with minimal cost.

The simulation results suggested that the distribution of the frequencies of the fixed mutation rates was similar to a bell shape, revealing that the optimum mutation rate will be maintained within an intermediate range under natural selection rather than be kept at a minimal one.

Thirty years on from the birth of thrash in San Francisco's Bay Area, Oozing Wound have created a modern, minimal mutation of the sound.

If the deleterious mutation rate is too high, asexuals will quickly go extinct.

The argument is that organisms with a deleterious mutation rate above a certain threshold must reproduce sexually.

It is conceivable, therefore, that when a population faces environmental challenges, it would be advantageous to accelerate the mutation rate.