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In [ 41] the authors present a computer simulation model that uses an agent-based system developed with NetLogo to mimic the development and progression of solid tumors.

This switch was to mimic the development cycles of Western games in the Call of Duty, Assassin's Creed and Battlefield series, as well as maintain fan-interest.

The Wayne model (Wayne & Hayes, 1996) for example, uses gradual oxygen depletion to mimic the development of the granuloma, and was recently employed by Muttucumaru and colleagues (2004).

Genetically-engineered mouse models (GEMMs) of cancer have been constructed to more closely mimic the development of human disease in a predictable manner [ 24].

As our animal model might mimic the development and progression of EGFR-amplified tumors in patients, we analyzed a tissue microarray from 206 GBM patients for EGFR amplification, protein expression and activation (pEGFR).

To mimic the development of human inflammation-associated lung fibrosis in mice, we trans-nasally administered bleomycin to gender-matched mice (8 12 weeks of age) harbouring gp130 mutations that bias intracellular signalling either towards the Stat1/3 or Erk1/2 signalling pathways in gp130 757F mice or gp130 ΔStat mice, respectively (Tebbutt et al, 2002) (Supporting Information Fig S1).

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Here we present a novel transgenic mouse model, APPSLPS1KI that closely mimics the development of AD-related neuropathological features including a significant hippocampal neuronal loss.

He also speculated on any follow-ups mimicking the development cycle of Grand Theft Auto, with a new release expected every two to three years.

Another commonly used method for neural induction is via EB formation in a chemically defined system including a minimum medium, which mimics the development of neural ectoderm cells in morphology and gene expression profiles[3], [5], [37].

This phase mimics the development of a predictive biomarker (see next section).

For in vitro studies, we chose a method of neurogenesis from adherent-monoculture of ESC, which sequentially mimics the development of cortical neurons over the course of 21 days of differentiation [ 74].

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