Sentence examples for migration of pathogenic from inspiring English sources

In vitro, we show that while the migration of pathogenic PLP-specific T cells to construct cultivated with or without stromal cells does not differ, their activation and proliferation are significantly suppressed in the presence of stromal cells.

The data presented above indirectly suggest a critical role for the GITR/GITRL interaction in the migration of pathogenic effector T cells to the target tissue.

The interaction between CCR6 and CCL20 plays an important role in the migration of pathogenic Th17 cells in arthritis, and a majority of Th17 cells express CCR6 [ 19].

Several chemokines have association with AD phenotype and among them, CCL17, CCL22, CCR4 have pivotal roles in migration of pathogenic immune cells (mainly CD4+ T cells) to the site of inflammation [ 34].

The identification of some of these traffic signals has proved to be of clinical importance as blocking these molecules reduces the migration of pathogenic immune cells into the CNS and proven beneficial for the treatment of MS. In contrast, induction or enhancement of immune cell trafficking signals on the BBB could be beneficial for the treatment of CNS infections or neoplasia.

As a first step we tracked the migration of highly pathogenic H5N1 during its evolutionary history.

In addition, C5a regulates the migration of IL-12+ dendritic cells to induce the development of pathogenic Th1 and Th17 cells in sepsis [ 80].

Also of special interest was the report by E. Mackow (Stony Brook, NY), on the selective inhibition of beta3-integrin directed endothelial cell migration by pathogenic hantaviruses.

This results in enhanced migration of neutrophils to the site of infection and promotes the clearance of pathogenic bacteria.

These macromolecules influence adhesion, migration, proliferation, and differentiation of eukaryotic cells [ 22], and they serve also as substrate for the attachment and internalization of pathogenic microorganisms [ 23, 24].

An understanding of the global migration dynamics of highly pathogenic avian influenza A(H5N1) virus is helpful for surveillance and disease prevention.