Sentence examples for might trigger apoptosis from inspiring English sources

Finally, a connectivity model concerning MAPK is proposed, summarizing how cold stress and MDR-1 might trigger apoptosis in resistant cell lines.

(2) Our favored explanation is that the malfunctioning of gene expression in the micronuclei might trigger apoptosis.

Additionally, the root extract also prevents elevation of sperm oxidative stress that might trigger apoptosis.

If unchecked, the UPR might trigger apoptosis, leading to photoreceptor death.

Furthermore, caspase-12 activation during excitotoxicity was inhibited when RyRs were blocked by ryanodine, indicating that AMPA-induced ER-Ca2+ release might trigger apoptosis through mitochondria-independent pathways.

TNF-α might trigger apoptosis in hepatocytes by signaling through the Fas-associated death-domain protein of the TNF receptor that activates caspases (Leist et al. 1996; Schuchmann et al. 2003).

Additionally, the PDT-induced defect of mitochondria and the release of Ca2+ into the cytoplasm might trigger cell apoptosis or necrosis, which may result in the cell morphology and cytoskeleton defects eventually.

The above observations implicated that PEE administration might trigger the apoptosis in T24 cells through death receptor signaling and mitochondrial damage pathway.

In conclusion, PEE treatment could suppress UBUC cell and might trigger the apoptosis in bladder cancer cell through death receptor signaling and mitochondrial damage pathway.

In these cells, low levels of caspase-8 could probably activate little caspase-3 that XIAP keeps in check preventing the apoptosis cascade, but when XIAP is targeted, the levels of caspase-3 might become enough to trigger apoptosis.

Because the precise molecular mechanism for the CIAPIN1 apoptosis signaling pathway is still unclear, there might be other different mechanisms to trigger apoptosis in different cell lines depending on the unique genetic context in the individual lines.