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On the other hand, also in humans, the latter mechanisms (driven by both genetic and environmental factors) might represent key variables underlying individual vulnerability to psychiatric disorders [9], [16], [77], [78].

We conclude that functional assimilation, high gene turnover and selection might represent key features of HGT events in nematodes.

The splenic RP and MZ-associated bridging channels might represent key sites for the activation of polyreactive B cells.

Thus, functional assimilation, remarkable gene turnover and selection might represent key features of horizontal gene transfer events in nematodes.

Date hubs, on the other hand, associate with different vertices in different conditions and might represent key regulators that orchestrate the activity of network modules according to the needs of a cell in specific circumstances.

Similar(55)

Among the corresponding mutants, 5 showed shortened and 21 showed increased maximal chronological lifespans; 15 of the latter mutants showed no further lifespan increase with rapamycin and might thus represent key targets downstream of TORC1.

Interestingly ILK1 increases the expression of VEGF which imply that ILK1 might represent a key molecule for a positive loop inducing angiogenesis and tumor grown.

Thus, immunomodulation might represent the key mechanism by which CSCs promote tumorigenic growth.

In conclusion, parathyroid hormone increased the fluorescence intensity of calcium ions in BMSCs, which might represent a key mechanism whereby BMSC proliferation is maintained.

Thus, we selected EMT signalling biomarkers, which might represent the key players in the initiation and progression of RLNM for RC, to construct our SVM model.

Therefore, despite advanced clinical approaches with surgery, radiotherapy and chemotherapy [ 54- 56], inhibition of angiogenesis might represent a key strategy in the treatments of gliomas.

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