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Agents which cause intracellular acidification at low pHe might have selective toxicity towards cells in tumours.
This observation raises hope that synthetic TLR3 ligands combined to IAP inhibitors might have selective effects on malignant cells.
We questioned how far hybridization between Microcebus griseorufus and M. murinus would be restricted to the presence of an intermediate habitat where hybrids might have selective advantages.
This situation demonstrates a fundamental principle often overlooked in the mapping of complex disorders: that genetic variants might have selective effects in specific populations depending upon the genetic and environmental background.
This observation suggests that, although the Beijing genotype as a whole might have selective advantages enabling its rapid dissemination, the XDR isolates are relatively less fit and do not propagate well.
Similar(55)
Viruses harbouring less deleterious mutations might have a selective advantage in a landscape of highly damaged viruses.
In theory, they might have been selective and not asked women who were dissatisfied with their care.
Second, phenotypically-suppressed cells might have a selective advantage in the stem cell niche in the meristem and over time outcompete those without suppressor mutations.
In that sense, carotenoids on seeds may have decreased because, e.g., less oxidative stress because of improved, and more predictable, supply of water and nutrients might have relaxed selective pressures over their metabolic pathways.
> -wrap-foot> To understand the genetic and genomic changes associated with chicken domestication, we searched for local reductions in heterozygosity that might have accompanied selective sweeps in the common ancestor of Silkie and L2.
While in the short run, asexual species might have a selective advantage, in the long run only those lineages survived that happened to maintain sexual reproduction sex being a relict from as early as the RNA world [ 54, 55].
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