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Using an analytical solution to Fick's Second Law where sorption is partitioned into macroscopic and microscopic domains, each with unique diffusion time constants, enables precise prediction of experimental sorption observations.
(D – F ) The optically uniform vesicular surface breaks up into a pattern of microscopic domains, which grow by collision and coalescence.
While large microscopic domains of co-existing liquid phases are thought to not exist in many living cells, a recent study reveals such domain texture in yeast vacuole membranes (Toulmay and Prinz, 2013).
The time-dependent process of the appearance and disappearance of large microscopic domains repeats itself multiple times (n > 10) over several tens of minutes ultimately producing a steady-state characterized by a fixed microstructure and a rounded boundary.
In this study, under conditions of nutrient deprivation, pH changes, and changes in the growth medium have been shown to segregate into microscopic domains in what appears to be a sterol-dependent manner, reminiscent of synthetic giant vesicles.
DOI: http://dx.doi.org/10.7554/eLife.03695.012 This tension and pressure-mediated appearance of the phase-separated state in osmotically swollen membranes, however, does not account for the oscillations in domain pattern: (1) why does the osmotically swollen vesicle characterized by large microscopic domains return to a homogeneous state, and (2) what prompts subsequent cycles of phase separation?
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But Humphreys appears to allow that it may have application outside this microscopic domain.
To solve the micro model, boundary conditions are required on the boundary of the microscopic domain.
However, machining of titanium in macroscopic or microscopic domain is a complex task either by conventional or nonconventional machining processes.
The different macroscopic non-linear behaviors of the ferroelectric polycrystals are attributed to different microscopic domain switching processes.
A multiscale approach of the problem is established distinguishing between macroscopic region domain (bone organ and scaffold) and microscopic domain (scaffold microstructure).
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