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The complete microarray gene list is included in Table S1.
Details on the microarray gene list are presented as supplementary data (Table S2).
Alternatives such using the full microarray gene list or full known gene set generally yielded even stronger prevalence biases (stronger prevalence list performance and stronger correlations between prevalence and true performance).
As reference we used the DNA microarray gene list and the results are shown in Figures 4 and 5.
The three columns under each comparison (gene list) represent, from left to right, the fold change (FC) from the microarray gene list, the FC for the quantitative reverse transcriptase PCR QPCRR) and the statistical significance from the QPCR (P value).
To examine the expression level of genes related to cAMP or G-protein, a total of 11 genes were found directly related to cAMP or G-protein in the microarray gene list.
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bThe fold change is the relative intensities for each gene from the microarray gene lists B10.Q versus B10.Q.
aThe fold change is the relative intensities for each gene from the microarray gene lists B10.Q versus B10.Q.
The databasing of such microarray gene lists thus allows for a systematic comparison of the results of various studies [ 48] in order to identify consistent expression patterns.
Examination of the microarray gene lists for growth factor and growth factor receptor genes affected by HDIs identified eight genes that could influence osteoblast growth, but only three were increased.
Although we do not use Unigene annotations of probes to identify the targeted genes (see discussion section for explanation) this allowed us to associate Entrez Gene ids with EST accession numbers, which are commonly used in microarray genes lists.
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