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The results are supported by microarray analysis, showing down-regulation of several fibrosis-related genes (Table 2).
These data were in full agreement with the microarray analysis, showing that flagellum-related genes are up-regulated in the D4 and D4 D9 mutants and down-regulated in the D9 mutant (Table 4).
The significantly higher expression of the SjIRs in the mammalian host also substantiates the conclusions of our recent microarray analysis showing that host insulin can be exploited by S. japonicum for growth and development [23].
This was verified by a microarray analysis showing that genes which are transcriptionally activated by HIF1A were upregulated in the EGFR-CD533 expressing tumors.
ATBF1 was an other candidate gene identified by our microarray analysis showing decreased mRNA expression in tumors with LOH at 16q.
The ten genes analyzed by transcript-specific qRT-PCR analysis corroborated the microarray analysis, showing correlation coefficients ranging from 0.710 to 0.988 (Additional file 2: Table S1).
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Microarray analysis showed that hypergravity up-regulated the expression of 403 genes to more than 2-fold.
Our gene microarray analysis showed that DRG G9a overexpression altered the expression of 5,234 genes, in which 2,903 genes were downregulated and 2,331 genes upregulated.
The observed migration is not likely due to epithelial mesenchymal transition because microarray analysis showed that epithelial mesenchymal transition marker gene expression was not altered (Supplementary Fig. 10).
A microarray analysis showed 330 genes regulated in the roots (p ⩽ 0.001) upon endogenous NO depletion.
M. marinum is closely related to M. tuberculosis, which causes tuberculosis in people.A microarray analysis showed that metabolism is profoundly affected in M. marinum-infected flies.
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