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We found spontaneous liver metastases developed in only three (25%) of 12 mice with local invasion of the reporter fragments.
The viral vectors (1 × 108 PFU) were respectively injected into the adductor magnus muscles of BALB/c mice with local hair depilated.
One should emphasize that there are clear sex differences in various characteristics of mice with local disruption of the GHR or with global GHR knockout.
By contrast, it is normal in mice lacking D2R and in dopamine-deficient mice with local production of dopamine in the dorsal striatum.
similarly, as shown in Fig. 5c, d and e (* p < 0.05, ** p < 0.01), the percent of mice with local lymph node metastasis in vehicle group could reach 80%% ~ 90%%, while reaching only 50%% in 37.5 mg/kg group and 20%% in 150 mg/kg group, respectively.
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In addition, PDT treated mice had equal or less metastatic lung colonies than comparable mice treated with local surgical excision of the primary LLC lesion.
The animals were divided into the following 3 groups: Group A 3 BALB/controltrol mice without mesenchymal stem cell implantation; Group B 3 mdx controls without mesenchymal stem cell implantation; Group C 3 mdx mice treated with local injections of mesenchymal stem cells.
Similar attenuation of inflammation has been shown in response to zymosan (a Toll-like receptor-2 agonist) in mice with reduced local and systemic signs of inflammation and organ dysfunction and lowered levels of TNF and IL-1β compared with control animals [ 67].
Mr. Giovanelli, whose cat-and-mouse history with local and federal law enforcement officials stretches across decades, is on parole for a 1989 racketeering conviction.
The delivery of systemically injected polymer rhodamine conjugates to solid tumors was investigated by in vivo fluorescence video microscopy of ovarian tumors implanted in dorsal skin fold window chambers in nude mice, with and without local hyperthermia.
Mice were kept at the MPI for Molecular Genetics mouse facility in compliance with local animal welfare laws, guidelines and policies.
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