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xenografts and SCID mice with intra-tibial xenografts.
(b) SPECT/MR images of SCID mice with intra-tibial xenograft in the left hind limb.
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Osseous tumours were established in SCID mice through intra-tibial injections of LNCaP cells in the left hind limb, and SPECT/CT images were performed after i.v. injection of 111In-DTPA-11B6.
Finally, the in vivo pro-OC activity of these cells was assessed in SCID mice after intra-tibial injections.
Two latencies were recorded per mouse with intra-trial separation of 30 seconds and maximum trial duration of 30 seconds.
213Bi-DTPA-[F3]2 was injected i.p. into mice with intra-peritoneal xenograft tumors.
C57BL/6 and CBAxC57BL/6 Tg mice with intra-hepatic expression of the NS3/4A proteins 17 were bred and maintained in-house.
Although this cell line is classified as a castration-resistant prostate cancer line, its growth rate was reduced in castrated mice compared with intact mice, in both subcutaneous and intra-tibial growth conditions.
The majority of combination therapy studies in breast cancer have used xenograft models, where human breast cancer cells are implanted in immunocompromised mice via intra-cardiac or intra-tibial injection.
Therefore the radiographs demonstrate a decrease in the overall extensive periosteal bone formation observed with the LuCaP 23.1 intra-tibial tumors by both ZOL alone and the combination of ZOL + docetaxel.
Treatment with PEDF was delayed until day 20 after intra-tibial inoculation with the SaOS-2 human osteosarcoma cell line.
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