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While BMAL1-deficient mice also exhibited robust FAA during restricted feeding in constant darkness, mice were hyperactive during food deprivation so it was not clear that FAA consistently occurred at the time of previously scheduled food availability.
Specifically, fRIM1/KA-cre+ mice were hyperactive during a 2-h test of locomotion.
Consistent with previous studies, 27 Scn1aRX/+ mice were hyperactive in the open field (see Fig 6D).
The results are however difficult to interpret since the mice were hyperactive.
Id2−/− mice were hyperactive at 1 and 3 months of age, but by 6 months showed reduced activity.
We found that Fabp7 KO mice were hyperactive with an anxiety-related trait, based on a battery of behavioral tests.
Similar(49)
One result, Costa has shown, is that the NMDA receptors of Ts65Dn mice are "hyperactive" — they overreact to stimuli.
A commentary by Elizabeth Pennisi published earlier this year in Science noted that germ-free mice are hyperactive, and that this behavior was reversed if the mice were colonized with specific bacteria introduced at a critical age.
We show that these new mutant mice are hyperactive when exposed to a new environment.
We questioned the functional consequences of these defects and report here that Dcx KO mice are hyperactive and exhibit spontaneous convulsive seizures.
In addition, mutant mice are hyperactive and suffer epileptic seizures similar to patients with CDFE.
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