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An empirically determined system calibration factor (i.e. µCi/mL/cps/voxel) for mice was derived by imaging a mouse-size cylinder containing 18F uniformly dispersed in water and used to convert voxel count rates to activity concentrations.

The embryonic stem cell line used in generation of the mice was derived from the 129S4 strain, and mice of the genetically most closely related commercially available 129 substrain, 129S1, were subsequently used for breeding [12].

The mouse strain background of Faah−/− mice was derived from breeders back-crossed onto a C57B1/6J background for 13 generations (Cravatt et al., 2001).

The loss of body weight in TB-con mice was derived from both loss of muscle mass and fat mass (e.g., epididymal fat).

Acute γ-secretase inhibition of Aβ production in plaque-free and plaque-rich mice suggested that Aβ 1-42) in the interstitial fluid of plaque-rich mice was derived primarily from Aβ 1-42 Aβ 1-42tered in brain parenchyma rather than from new biosequestered

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Bone marrow-derived macrophages from BALB/c, C57BL/6 or NZB mice were derived and cultured as described [ 91].

Nrf2−/−/HLL mice were derived in a similar fashion.

C57BL/6J mice from which these mice were derived were used as control mice.

NonTg mice were derived from the original mouse line with the same genetic background.

KΔ75 loss-of-function mice were derived from eight backcrosses with C57BL/6 mice [31].

p53−/−p73+/− mice were derived from crosses between the double heterozygous animals.

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