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After 3 weeks, the researchers induced seizures in the mice using either a drug injection or electrical stimulation of the brain.
Excess inflammatory cell infiltration and neointimal hyperplasia (accelerated plaque growth) were detected in aortic allograft transplants at 4 weeks follow up in control, saline treated, wild type (WT) mice, using either C57Bl/6 donor to Balb/c recipient mice (Fig. 1A,E) or Balb/c donor to C57Bl/6 recipient mice (Fig. 1 C, E, n = 19).
Supporting the relevance of this approach, it was shown that inhibition of Hif1 in mice using either pharmacological inhibition or conditional gene deletion significantly reduces airway inflammation in models of asthma [ 24, 25].
Menin expression was assessed in the different prostatic lobes from Men1 wild-type mice using either IHC for menin or double IF with antibodies against menin and p63, a basal epithelial cell marker.
Protein and RNA were then isolated from IECs of STAT5IEC WT and STAT5IEC KO mice using either EDTA-based or LCM to determine pMLC levels and TJ proteins (TJPs) expression.
Pre-operative X-irradiation of s.c. implanted first-generation mammary tumours in C3H mice, using either 500 rad or two fractions of 350 rad, produced no improvement in the success of surgery in causing local control or in reduction of distant metastases.
Similar(47)
Old studies on Edar mutant mice used either Edardl [1], [9] or Edarsleek [3] mice.
As expected, no differences in cone density were found for the wild-type (wt) mouse using either methods.
We present high-throughput screening (HTS) data for 3 762 distinct global gene knockout (KO) mouse lines with viable adult homozygous mice generated using either gene-trap or homologous recombination technologies.
The development of accessory pathways has been demonstrated in mice by using either activation of notch signaling or inactivation of Tbx2, indicating that dysregulation of the cell signaling pathways that are essential for the development of the AV canal and the AV node may be responsible for the Wolff-Parkinson-White syndrome.
The pathogenic role of B cells in SLE has been highlighted by mouse studies using either B-cell-deficient mice or B-cell depletion [ 25, 26].
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