Sentence examples for mice to block from inspiring English sources

To find out, the team genetically modified mice to block production of Nppb in TRPV1 neurons, then injected the skin on their shoulders with a range of itch-inducing compounds, including histamine, an inflammatory molecule involved in immune responses, and the malaria drug chloroquine.

Furthermore, anti-PD-1 monotherapy enabled wild-type mice to block tumor growth to similar levels as SKAP55-deficient mice (Fig 6C, green vs. purple lines).

We will use Col2CreER Mmp13 fx/fx (Mmp13 Col2ER) mice to block Mmp13 expression in chondrocytes and use MMP13 inhibitors to inhibit MMP13 activity.

Besides the conventional strategies utilizing the caspase inhibitors and gene knockout mice to block apoptosis, several other therapeutic regimens may have pivotal roles in protection from apoptosis involving the cellular machineries.

Farnesyl transferase inhibitors (FTIs) have been applied to progeroid cells and to Zmpste24-/ mice to block the prenylation reaction since it is believed that a major phenotype-inducing element of progerin and FC-prelamin A is the farnesyl moiety [ 14, 29].

This phenomenon can also account for the death of one of nine animals in experiment 2, in which a high dose of BN antagonist RC-3095 was injected into nude mice to block BN receptors, before each of the three injections of AN-215 at 150 nmol kg−1 of BW.

For example, Walker L.S.K. et al (JI 2003) use an elegant CTLA-4 transgenic mouse to block CD80/86 after GC induction, resulting in a larger GC response which is the opposite of what we observe in our Cd28 flox/flox Ox40 cre/+ mice in which CD28 alone is targeted.

Paraformaldehyde (PFA, 4%) fixed frozen sections of brain ventricles (from a juvenile male) and cultured ependymal cells were permeabilized with 0.1 0.5% Triton X-100, blocked in 5% NGS, 1% BSA, 0.1% Triton X-100, 0.05% Tween20, and incubated with unconjugated Fab fragment goat anti-mouse (Jackson Immuno Research) to block endogenous mouse IgGs.

Giving the mice drugs to block opioids, which are used in rehab clinics, led to withdrawal symptoms including shaking and tremors.

Lavage fluid cell suspensions (200 μL) were incubated for 20 min with rat anti-mouse CD16/CD32 to block nonspecific Fc binding then stained with anti-mouse Ly-6G (1A8) for 30 min. Brain cell suspensions were prepared by enzymatic digestion and density gradient centrifugation and cells incubated with anti-CD16/CD32 anti-CD16/CD32g with anti-mouse Ly6G-Pacific before

A long pass filter was interposed between the microscope lens and the mouse eye to block any light of less than 665 nm wavelength.