Sentence examples for mice that led from inspiring English sources

The decreased keratinocyte proliferation and increased squamous differentiation patterns observed in transgenic epidermis have a direct correlation with our observations during skin carcinogenesis of K5-VILIP-1 mice that led to a decreased sensitivity to skin carcinogenesis.

These DKO mice were significantly younger (31±2 wks; range  = 25 38 wks; n = 10) than the Il10−/− mice studied (36±1 wks; range 34 36 wks; n = 15; p = 0.02) due to more frequent occurrence of rectal prolapse (an indicator of severe IBD) in DKO mice that led to euthanasia for humane reasons prior to the planned study endpoint.

Toward this aim, a panel of genes (Text S1) that are frequently altered in human NSCLC was examined in a random collection of tumors from ten mice that led to the identification of frequent point mutations in K-Ras and LKB1 genes (Figure 3B).

By using a liver-specific TAF4 mutant mouse line, the authors observed several severe liver failures in P12 to P21 mice that led to lethality.

We previously reported that administration of estradiol to pregnant mice that led to a similar elevation in fetal serum estradiol, and also maternal administration of low doses of estrogenic drugs, produced an increase in prostate gland number and size in male offspring maintained on PMI 5008/5001 feed (Timms et al. 2005; vom Saal et al. 1997).

We have identified a spontaneous mutation in mice that leads to adult onset, bilateral, progressive cerebral ischemia.

Thus, delivery of XMRV antigens clearly elicits a humoral immune response in mice that leads to the production of XMRV-specific binding antibodies and NAb.

Recently, we described major oxidative phosphorylation defects in the Plp1tg mice that lead to 50% reduction of tissue ATP and loss of mitochondrial membrane potential.

We used 1 3-day old faeces, which will not contain infectious stages of many of the parasites, to test whether wild mice can detect cues in the faeces of parasitized mice that lead them to avoid feeding or nesting.

Furthermore, our MUNE results demonstrate an expansion of individual motor unit territory in the SMNΔ7 mice that leads to each motor unit representing a larger percentage of the total output.

On the other hand, overexpression of CSF-1 in wild-type mice that leads to an early induction of macrophage infiltration into premalignant lesions accompanied by neoangiogenesis, accelerates their transition to malignancy [ 52].