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I also tested the relative use by mice of four microsite types: CWD, pits, woody brush, and open ground.
We studied ocular dominance plasticity in the visual cortex using mice of four different age groups: PD25, PD95, PD130 and PD215 (see Methods for details).
Adult male and female mice of four genotypes were used in this study, summarized in Table 2. Recessive yellow mice, Mc1re, lack a functional MC1R.
In each 8-plex iTRAQ experiment, combined left and right hippocampi of wildtype (WT) and transgenic (TG) mice of four different ages were labeled with one of the eight iTRAQ labels.
An antisense transcript is rhythmically transcribed to Per2 RNA (plus strand), peaking at ZT4. DOI: http://dx.doi.org/10.7554/eLife.00011.020 To validate this interpretation, we assayed the pre-mRNA levels in Bmal1−/− mice of four clock genes that exhibit different phases of transcription in wild-type mice.
In order to generate experimental animals, Grb10 m/+ females were crossed with Dlk1 +/p male mice, thereby taking advantage of the imprinted status of each gene to generate in equal proportions mice of four genotypes; wild type (WT or Grb10 +/+ ; Dlk1 +/+ ), Grb10 m/+ and Dlk1 +/p single knockouts, and Grb10 m/+ /Dlk1 +/p double knockouts.
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Knockout (KO) mice of two genes (IMPA1 or Slc5a3), each encoding for a protein related to inositol metabolism, were studied in comparison with lithium-treated mice.
As a result, we found that a number of miRNAs were significantly altered in the livers of mice of two groups (P < 0.05).
Delivery into mice of two HEV ORF2 genes via a papillomavirus VLP was very effective in the induction of anti-HEV antibodies.
To assess the impact of BCG on HBV immunization, mice of three different age groups were immunized subcutaneously with, BCG, HBV, (BCG + HBV) into the same site; or BCG and HBV injected into separate sites.
CD1Nu/Nu mice of eight weeks were purchased from Charles River (Sulzfeld, Germany).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com