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In contrast, 1.5 hours after the end of the contextual fear conditioning, the whole population of c-fos+/NeuN+ neurons significantly decreased in PC3/Tis21-null mice, of about 21% (p = 0.006, Figure 6F).

C57BL/6 mice of about 20 grams were purchased from Jackson Laboratory (Bar Harbor, ME, USA).

Additionally, although defective T cell differentiation can be detected in newborn PI3Kγ-deficient mice, differences decrease in mice of about one month of age [ 12].

In general, Purkinje cells in CDKN1A−/− mice of about 1 year of age showed weaker staining intensities for γH2A.X, phospho-p38MAPK, 4-HNE and IL-6 in direct comparison with parallel CDKN1A+/+ mice of the same age (Fig. 6A).

The study of the gastric ulcerogenic properties has been carried out in healthy CF1 female mice of about 30 g provided by Facultad de Ciencias Veterinarias, Universidad Nacional de La Pampa.

Given that a total blood volume of the nude mice of about 20 g (body weight) is 1.5 ml, we expected that TfR-lytic may exert enough antitumor effects at a dose of approximately 2.8 to 5.6 mg/kg.

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As shown in Figure  5A, Tregs from NOD mice inhibited less than 10% of 8.3 killing; while Tregs from B6 mice had inhibitory activity of about 20%.

In addition, using sgRNAs targeting two separate sites in the Mecp2 gene, we produced mice harboring the predicted deletions of about 700 bps.

We generated a mapping panel of about 200 mice, isolated the DNA and started collecting probes.

Weiss et al. estimated that one lineage of TH-MYCN transgenic mice had about 4 copies of the transgene by Southern blot analysis [3].

However, white adipose tissues (WAT) were markedly reduced in Rcan2−/− mice at about 60% of the wild-type (Figure 2F).

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