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All together, we conclude that oncogene-induced senescence in mice may occur in the absence of a detectable DNA damage response.

This observation suggests that PDE5I can ameliorate the progress of the disease mainly through its myofiber protective function, but not through upregulation of regeneration and that regeneration of myofibers often observed in mdx mice may occur secondarily to upregulated muscle degeneration.

Alternatively, the commitment to the transition of WAT into BAT-like tissue in FSP27-/ mice may occur before differentiation at the precursor stage.

Neuroprotection of the herbal formula B401 in the brain of R6/2 mice may occur via inhibition of oxidative stress and apoptosis.

These findings demonstrate that micrometastasis in glomeruli in mice may occur through interactions between α5 β1 on tumour cells and fibronectin in the glomeruli.

Residual immune responses to xenografted tumours in nude/SCID mice may occur and the sex of the host should be considered, particularly for hormone-responsive tumours such as breast and prostate.

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However, after skin closure and re-placement of the mouse into the cage death of the mouse may occur in the next 24 hours.

The results are discussed in relation in those of Pound and Withers (1963) and others, who found that mitotic stimulation at the time of urethane initiating action raised the ultimate tumour incidence; and the inference is drawn that initiating action in mouse skin may occur during the M phase, rather than during the G1, S, or G2 phases, as suggested by others.

Instead, the accumulation of IFNγ+, IL-6+ and IL-17A+ IEL cells in prolapsed CD4cre:PP4f/f mice may only occur during the latter phase of colitis pathogenesis.

For example, PTHrP gene null mice exhibit craniofacial anomalies that may occur as a consequence of altered intramembranous ossification.

Previous studies on changes in gene expression in the hypothalamus of FGF21-dosed DIO mice have shown that hyperphagia may occur via a compensatory nutrient, sensing-mediated process [ 18].

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