Sentence examples for mice develop premature from inspiring English sources

The objective of this study was to determine whether heterozygous (Dmm/+) mice develop premature OA, and could therefore serve as an animal model for studying the molecular pathways leading to OA.

Moreover, the decline in HMGB2 levels was associated with increased chondrocyte death, and HMGB2-deleted mice developed premature OA [ 45].

Previously we reported that Bmal1 −/− mice developed premature aging and had dramatically reduced lifespan [ 13]; thus, our current data suggest that the reduced longevity in Bmal1 −/− mice may result from the constitutively elevated mTORC1 signaling.

In a noteworthy animal experiment published earlier this year, Japanese scientists bred mice to develop premature knee arthritis, then dosed some with levels of MSM equivalent to that found in most over-the-counter preparations for people, while others received 10 times as much MSM, and others none.

These results suggest that Bax deficiency was able to decrease the mortality of ku70 −/− mice that have been reported to develop premature aging phenotypes.

These results suggested that the GMF-TG mice developed mild premature aging phenotypes.

These mice developed a premature ageing phenotype including kyphosis, weight loss and osteoporosis, caused by an increase in somatic mtDNA mutations, including both point mutations and deletions (Trifunovic et al., 2004).

These transgenic mice develop myocardial inflammation with premature death from heart failure in association with extracellular matrix remodeling (Kubota et al., 1997; Li et al., 2000).