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Exact(19)
This data indicates that L. donovani mutants probably have a significantly reduced rate of metabolism of MG as compared to the wild-type parasites suggesting that the glyoxalase pathway is the dominant route for detoxification of MG in L. donovani.
The data show that rivastigmine (1.5 and 3 mg), as compared to placebo, did not significantly alter total choices for methamphetamine (p = 0.150).
Thus, incident cancers were less frequent among those randomized to suvorexant, particularly less than 30 mg as compared to placebo.
In addition, the use of prucalopride 2 or 4 mg, as compared with placebo, significantly reduced the use of bisacodyl tablets taken per week (P<0.001).
The median dose of SSRI for children receiving combination treatment was 150 mg, as compared to 200 mg for children receiving sertraline alone or placebo [ 2].
With 0.125 mg pramipexole the IRLS score was reduced by 60%, by 78% with 0.5 mg and 75% with 0.75 mg as compared with placebo (P<0.0001).
Similar(41)
Patients treated with TMZ alone had the highest levels, consistent with their daily dose of 200 mg m−2 as compared to the 75 125 mg m−2 administered within LM/TMZ.
The lack of fit to a sigmoid Emax model might be explained by the narrower dose range in this study (40 60 mg m−2) as compared to the previous study (20 80 mg m−2) that resulted in a narrower range of exposure.
This was also confirmed by the higher protein-binding values of [68Ga]AAZTA-MG as compared to its 177Lu counterpart.
Our results appear to be consistent with others, as we also observed higher formation of dFdCTP at lower ROI (ROI<25 mg m−2 min−1) as compared with ROI>25 mg m−2 m−2−1.
Activated carbon consumption was also less in case of DBF (40 mg/N m3) as compared to SBF which discharged about 100 mg/N m3.
Related(19)
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