Sentence examples for methods have serious from inspiring English sources

Standard supplier segmentation methods have serious shortcomings, for instance because they fail to make a proper connection between supplier segmentation and other supplier-related activities such as supplier selection and development.

All of these alternative methods have serious limitations and do not always produce reproducible results.

These methods have serious limitations whenever multiple parameters have unknown values, which is usually the case.

However, these methods have serious drawbacks because gene expression can be affected by several factors, including the developmental stage of the plants.

Now a report released by the National Research Council more or less suggests that the method has serious flaws.

This method has serious drawbacks, primarily related to the subjectivity in estimating initial rates from experimental data.

But Elyn Rykken, a mathematician at Muhlenberg College in Allentown, Pennsylvania, and colleagues at two other colleges say that the method has serious defects.

However, the ellipsoidal vesicles made by the traditional method seemed to be more dispersed, but this method has serious issues of reproducibility and repeatability, which makes the supercritical process more attractive than the conventional one.

Each method has serious drawbacks, such that neither by itself is ideal.

However, this method has serious disadvantages associated with a lack of internal standards that can affect the quantitation of sweeteners.

These first generation methods may have serious weaknesses, which have been discussed by Tanskanen et al. [ 11].