Sentence examples for methods have major from inspiring English sources

Software based drug discovery and development methods have major role in the development of bioactive compounds for over last three decades.

Efforts have been made to improve the water stability of electrospun protein scaffolds using cross-linking and other approaches, but the current methods have major limitations, such as cytotoxicity and low efficiency.

Persistence of gastrointestinal nematode (GIN) infection and the related control methods have major impacts on the sheep industry worldwide [ 1].

Persistence of gastrointestinal nematode (GIN) infection and the related control methods have major impacts on the sheep industry worldwide.

These methods have major drawbacks that render them non-applicable in large-scale PPI prediction, namely the amount of time, associated cost and minimal protein interaction network coverage per run.

A prerequisite is the reproducibility of senescence-associated gene expression changes in different MSC preparations, whereas techniques for cell isolation, culture media and cell culture methods have major impact on the composition of MSC and their gene expression profiles [ 35- 37].

Our flow cytometry method has major advantages.

In addition, production methods can have major impacts on the evolution of the pathogen used for biological control; isolates cultured on artificial media can lose their pathogenicity for target hosts, and can lose natural variation, which might decrease their effectiveness in the field.

These could be achieved by choosing the adequate conditions, from a myriad of possibilities, being aware that slight changes in the preparation method could have major impact on the final material.

Participants' evaluations of the research method employed may have major implications for their willingness to disclose personal information and to participate in future (health services) research.

These published methods have three major limitations.