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It aims to transform traditional conservation methods by including the value of "ecosystem services" in business, community and government decisions.
We have clarified these points in the main text, and in Materials and methods by including a section called "DNA methylation differentiation metric".
This method is identical to that previously validated in a study of the ancestry of hemochromatosis probands [ 17]; in part, this method was modified from previously reported methods by including only the country of birth of grandparents [ 6, 14, 19].
Considering an improvement of other methods by including the graph information (as in [ 15]) we expect that it might give a better result for the tree partitioning algorithm as well.
Therefore, it is necessary to optimize CTC detection methods by including markers that are not repressed during that EMT but that still allow CTCs to be distinguished from the surrounding blood cells.
This method is identical to that previously described [ 17]; in part, this method was modified from previously reported methods by including only the country of birth of grandparents [ 14, 19].
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We discuss an extension of the method by including information about the amino acid sequence.
In the future, we will enhance the proposed method by including the effect of tissue deformation and relaxation.
Kissling et al. [10] extended the JHD method by including a 1-D velocity model as a parameter in inversion.
The approach extends the standard SIMP method by including the normalized norm of the spatial gradient of the design field into the material interpolation function, enforcing coating material at interfaces by attributing particular properties.
Thus, it appears that co-occurrence-based methods can detect a smaller number of PPIs with a somewhat higher accuracy, but the concept profile method, by including indirect evidence, can predict more PPIs and is therefore likely to be more valuable for actual knowledge discovery.
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