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The results of these studies have been equivocal, a phenomenon largely attributable to methodologic differences in study design and patient selection.
Although some nonexperimental studies suggest that statin use may reduce postsurgical AKI, methodologic differences in study designs leave uncertainty regarding the reality or magnitude of the effect.
These conflicting results might reflect methodologic differences in identifying human Treg, as no universally acceptable marker has been defined for these cells.
The difference might have been related to the methodologic differences in nursing and medical schools.
Methodologic differences in study design may explain the disparities in the results between the New Mexico and Minnesota cohorts.
The reasons for this difference may include random population variation, sex differences between the groups, or methodologic differences in the techniques used to measure cardiac responses.
Similar(51)
Methodologic differences between in vitro models and the inherent limitations of in vitro modeling may explain the discordant results on the significance of APC signaling through PAR1.
These inconsistencies may be due to methodologic differences or to differences in exposure.
Geographic variation or methodologic differences may account for the slight difference in reported prevalence.
This discrepancy could be due to regional differences in As contamination or from methodologic differences between the two study designs, because the Watanabe study employed a market basket technique to estimated food-derived exposure and we used a duplicate diet methodology that analyzed As in cooked, ready-to-eat food.
Despite these methodologic differences, their results were consistent with ours in that exogenous pulmonary surfactant was found to have no significant effect on mortality (relative risk 0.93; 95% CI 0.77, 1.12).
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