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Instead of the Li battery chemistry, methodical differences in LCA quantification seem to cause data deviations [49]: While the 'bottom-up' method of, e.g., Notter, Althaus, and Ishihara leads to lower CO2-equivalent emissions, a 'top-down' approach (Zackrisson and Frischknecht) seems to generate higher results (Table 4).
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Because of methodical differences, a direct comparison of impairments reported in different studies is difficult.
These differences might be caused by methodical differences such as the use of different antibodies, yet may be explained by the limited number of healthy cases in our study also.
Another study detected more differences in gene expression and histone modification profiles between hES and hiPSCs generated by different laboratories, suggesting that obviously methodical differences between separate studies rather than differences between both pluripotent cell types have to be considered (Newman and Cooper 2010).
Currently, it remains unclear whether these diverse results reflect entity-depending differences in CAR expression or might solely be caused by methodical differences.
This might be due to cell type specific differences and methodical differences.
The reasons for these differences may thus be population-related, or may reflect methodical differences.
Underlying methodical differences (radioimmunoassay versus immunofluorescence assay versus ELISA) might contribute to that phenomenon.
The authors attributed this discrepancy to methodical differences which cannot be excluded.
We assume that methodical differences between the questionnaires used (clinical interview vs. self-report scale) might have caused these results.
However, these findings may be attributed to the methodical difference that studies included in this review did not consequently exclude dementia cases from the samples.
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