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External noise was removed with the signal space separation method implemented with max filter software (Taulu et al., 2004).

Our model was also compared with grid method implemented with Python toolkit (grid.py) shipped with libsvm [ 61] for parameter optimization.

The basic information flow is very similar to the one which is depicted for the method implemented with HTML Frames in Fig.  6.

Even though mentioned as out of scope, it would still be useful to have a simple normalization method implemented with HiCUP.

The transcripts count was normalized by the trimmed-mean of M values (TMM) normalization method implemented with edgeR, and the 6 PAG and 6 cortex samples were treated as replicas for the two brain regions respectively during differential expression analysis.

Divergence times, based on gene divergence between lineages rather than speciation times, were inferred using the relaxed clock approach via the approximate likelihood method implemented with PAML's mcmctree program (Yang 2007).

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Mean field and beyond mean field methods implemented with the D1S force are used in large scale calculations to study the structure properties of fifty five even even actinides at normal and isomeric potential deformations.

Bayesian methods implemented with the computer program MrBayes v3.1.1 [32], [32] were applied to generate the dendrograms and to assess statistical supports for the branches from 16,000 trees generated from the original dataset.

Phylogenetic trees were generated by using MEGA version 5.0 (www.megasoftware.net) neighbor-joining methods implemented with 1,000 bootstrap replicates.

Lymphocytes count for all participants used flux cytometry methods implemented with BD FASCOUNT automate (BD Biosciences, Le pont de Claix, France).

Enrichment of predicted protein domains in each gene list was determined by a hypergeometric distribution with adjustment for multiple hypotheses testing by resampling methods implemented with FuncAssociate 2.0 using 10,000 simulations (Berriz et al. 2009).

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