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On Benchmark v4.0, our method has average I rmsd value of 3.31 Å and overall F nat value of 63%.

On CAPRI targets, our method has average I rmsd value of 3.46 Å and overall F nat value of 45%.

On Benchmark v4.0, our method has average I rmsd value of 3.31 Å and overall F nat value of 63%, which improves upon I rmsd of 3.89 Å and F nat of 49% for ZRANK, and I rmsd of 3.99 Å and F nat of 46% for ClusPro.

On CAPRI targets, our method has average I rmsd value of 3.46 Å and overall F nat value of 45%, which improves upon Irmsd of 4.18 Å and F nat of 40% for ZRANK, and I rmsd of Å and F nat of 32% for ClusPro.

On the CAPRI targets, our method has average I rmsd value of 3.46 Å and overall F nat value of 45%, which improves upon I rmsd of 4.18 Å and F nat of 40% for ZRANK, and I rmsd of 5.12 Å and F nat of 32% for ClusPro.

Similar(55)

Contigs from the seedling library (TUM25), which was sequenced by the pyrosequencing method, had the greatest average depth (14.9); contigs from the other libraries, which were sequenced by the Sanger method, had average depths ranging from 3.06 to 3.39 (Additional file 8: Table S4).

Here both methods have average RMSDs of over 10 Å, mainly due to large regions of the targets not aligned to a template in the 'hard' and 'hardest' test sets.

We also found that more than 98% of all experimental Xl-PSIDs that were designated " A" by the Affymetrix GCOS software (see Methods) had average intensity levels below four (n = 3269, see Additional file 1).

In this case of simple dynamics, our method has an average of 0.07, whereas the best ITK method has an average (normalized by nuclei diameter) of 0.10.

In this case, our method has an average (normalized by nuclei diameter) of 0.16, and the best ITK method has an average of 0.32. Figure 4A and Table 2 also show that ∼ of the nuclei are assigned to the wrong location using our method (Supplementary Fig. S1 shows an enlarged view of the location exhibiting the largest error).

Experimental results show that this method has an average accuracy of 90% and works with JPEG compression.

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