In this work, a novel method for surrogate-based feasibility analysis based on kriging metamodels will be presented.
The statistical methods for surrogate end point evaluation were used to explore which markers explained the association between gingival and retinal hemorrhaging (3).
We developed an efficient and universal method for generating surrogate or therapeutic antibodies against "difficult antigens" to facilitate the development of therapeutic antibodies.
Diffusion-weighted imaging (DWI) has been extensively used as an imaging method that yields surrogate parameters for tumor cellularity and proliferation and may be used to monitor treatment response in the brain and the abdomen[ 1 4].
However, while some encouraging epidemiologic and retrospective data exists for current methods of surrogate platelet testing for aspirin, these data lack sufficient rigor to inform clinical decision making, particularly in the setting of primary prevention (32, 33, 40).
Finally, considering that lipid modifications of proteins are of general importance for cellular signaling, the method reported herein for surrogate lipidation in place of native cysteine palmitoylation should have broad applicability to other lipidated proteins.
Mokeichev et al. (2007) [21] proposed three new methods for creating surrogate data of intracellular traces, and their results did not reject the null hypothesis that repeats of cortical activity are stochastically generated.
