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The statistical methods for surrogate end point evaluation were used to explore which markers explained the association between gingival and retinal hemorrhaging (3).
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Figure 7 Results of the proposed method for surrogate TS-50 AP mine.
Figure 6 Results of the proposed method for surrogate M-14 AP mine.
This paper presents a two-stage multi-fidelity (or named variable fidelity) method for surrogate models in honeycomb crashworthiness design.
It has been argued that there is no method for surrogate testing of repeated patterns of spontaneous activity that will satisfy every researcher.
In this work, a novel method for surrogate-based feasibility analysis based on kriging metamodels will be presented.
Mokeichev et al. (2007) [21] proposed three new methods for creating surrogate data of intracellular traces, and their results did not reject the null hypothesis that repeats of cortical activity are stochastically generated.
23 A detailed discussion of statistical methods for validating surrogate outcomes is out of scope for this article but some references are provided here.
However, while some encouraging epidemiologic and retrospective data exists for current methods of surrogate platelet testing for aspirin, these data lack sufficient rigor to inform clinical decision making, particularly in the setting of primary prevention (32, 33, 40).
We developed an efficient and universal method for generating surrogate or therapeutic antibodies against "difficult antigens" to facilitate the development of therapeutic antibodies.
Finally, considering that lipid modifications of proteins are of general importance for cellular signaling, the method reported herein for surrogate lipidation in place of native cysteine palmitoylation should have broad applicability to other lipidated proteins.
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