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Rather than to fragment the original molecule, our fragmentation method first builds an intermediate reduced graph where all the nodes represent a structural unit of the original molecule.
Rather than fragment the original molecule, the fragmentation method first builds an intermediate reduced graph where all the nodes represent a structural unit of the original molecule.
The method first builds an approximate map (or model) of the folding energy landscape from which the population kinetics are analyzed by solving the master equation on the map.
Octree (OCT [12]: This two-phase method first builds an octree (a tree data structure in which each internal node has up to eight children) that represents the color distribution of the input image and then, starting from the bottom of the tree, prunes the tree by merging its nodes until C colors are obtained.
In contrast to the approach favored by previous clustering based methods, which clusters genes by co-expression information and finds over-represented motifs for each cluster, our method first builds a gene co-expression network, and then searches for putative cis-regulatory elements that are enriched in the neighborhood for each individual gene on the network.
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The constraint-based methods first build the skeleton of the network (undirected graph) by a set of dependence and independence relationships.
The constraint-based methods first build a skeleton of the network (undirected graph) by a set of dependence and independence relationships.
Sailfish is a lightweight method: it first builds a unique index of all k-mers that appear at least once in the transcriptome, counts the occurrences of the k-mers in the RNA-Seq fragments and quantifies the transcripts by the number of occurrences of the k-mers through an EM algorithm.
In our method, we first build a weighted PPI network to select seeds.
Based on the predicted miRNA-target relationship predicted from the PITA method, we first built a miRNA-mRNA network of 32 differential miRNAs and 626 mRNAs (311 down-regulated and 325 up-regulated).
Our approach also offers rapid structural annotation for mutations in proteins vis-à-vis methods that first build a 3D model of a sequence followed by mapping of the mutations.
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procedure first builds
approach first builds
method first constructs
method first creates
method first calculates
method first trains
method first estimates
method first utilizes
method first selects
method first establishes
method first determines
method first optimizes
method first extracts
method first produces
method first detects
method first converts
method first performs
method first normalizes
method first transforms
method first computes
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