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Based on the developmental origins of the health and disease hypothesis or fetal programming (4), the intrauterine environment represents a time when changes in maternal metabolism may affect distant metabolic dysfunction in the offspring mediated through physiological and/or epigenetic mechanisms.
Statistical associations between gut microbes and metabolic diseases such as diabetes have led to the concept that microbial metabolism may affect host metabolism [ 17].
Altered bile acid secretion/absorption and/or metabolism may affect gastrointestinal physiology in those with FGIDs.
Researchers speculate that many hormones and substances produced by metabolism may affect sleep.
Single nucleotide polymorphisms (SNPs) located in genes encoding enzymes of the folate and choline metabolism may affect DNA methyltransferase activity.
In addition, biological evidence indicates that dysregulation of insulin metabolism may affect amyloid-β accumulation and degradation [38].
Similar(45)
Our novel findings regarding p53 regulatory function during adipogenesis suggest its possible influence on fatty acid metabolism, which may affect energy production, obesity and membrane synthesis.
Hence, the hepatic metabolisms as well as the gut flora and to a lesser extent the kidney are involved in its metabolism and may affect the urobilinogen plasma levels in subjects with reduced insulin sensitivity.
Metformin alters lactate metabolism, and may affect its prognostic value.
Thus, since ACAA2 is also involved in the pathway of fat metabolism, it may affect Weight.
MIF may function as a direct regulator of energy metabolism, and may affect adiposity as a proinflammatory cytokine in the manner of TNF-α.
Related(20)
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