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Cigarette smoke had a greater impact on the RPE than Bruch membrane, which suggests that multiple factors are involved in the development of the full blown AMD phenotype.
Positive immunofluorescent staining was seen along the whole cell membrane, which suggests that AE4 is localized in both the luminal and basolateral membranes.
Instead, these neurons contain proteins that can transport GABA across the cell membrane, which suggests that the neurons collect GABA from the extracellular fluid that surrounds them.
Moreover, under steady-state conditions, PLD1 has a predominently perinuclear location, whereas PLD2 is found at the plasma membrane, which suggests that the isoforms have different biological functions [ 1- 3].
The same study, however, found that macrophage depletion does not prevent endometrial cells from implanting onto the peritoneal membrane, which suggests different mechanisms are involved in the process of implantation in the pathogenesis of endometriosis.
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The cauliflower dlp of ca. 65 kDa (probably corresponding to wheat 63 kDa protein) was removed from the membranes, which suggests its rather peripheral localisation on the external side of the outer mitochondrial membrane.
GRO-α was not detected in the supernatant of infected DC but slight differences between H37Rv- and Beijing-infected cell supernatants were observed for the "GRO" spot on the membranes, which suggest that cells may differentially secrete either GRO-β/MIP-2α/CXCL2 or GRO-γ/MIP-2β/CXCL3 or both.
STAMP1 (six transmembrane protein of prostate 1), also known as STEAP2, also overexpressed in prostate cancer, has been located in the trans-Golgi network and shuttles to plasma membranes, which suggest a role in the secretory/endocytic pathways [ 3, 4].
The ability of Lpd850−1250aa to directly interact with polymeric actin extends the canonical model of Lpd membrane localization, which suggests that Lpd targets the plasma membrane by binding to PI 3,4 P2 and/or small GTPases (Krause et al., 2004).
As the only between-group differences concerned voluntary contractions, they are probably more related to central motor control failure than muscle membrane alterations, which suggests pathological muscle fibre remodelling related to altered suprasegmental control.
It should be pointed out that preincubated with NAC did not prevent Os-induced drop in mitochondrial membrane potential, which suggests that Os might be targeting mitochondria in a manner independent of ROS production.
Related(20)
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