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Exact(8)
The concomitant endosomal buffering effect and increased polymer endosomal membrane interactions are considered to lead to increased protein delivery into the cytosol.
Membrane interactions are also essential in controlling cell survival and proliferation, and alterations in membrane composition and function accompany cancer development [2].
The photolysis achieved with RBCs would therefore suggest that binding to heparan sulfate proteoglycans is not required for efficient photosensitization and that other membrane interactions are involved.
The roles of QS acyl chain length (C10 to C14) and cholesterol in membrane interactions are also investigated and the potential roles of membrane microdomains (or rafts) in immune modulation are discussed.
While membrane interactions are important for these peptides [44], confocal microscopy data obtained for the Combi peptide and several analogs show that they can rapidly become localized in the cytoplasm of bacterial cells, which suggests that they act on intracellular targets and that they are not strongly membrane-active [9], [45].
Membrane interactions are essential for transmembrane chemoreceptor array formation and function.
Similar(52)
α-synuclein membrane interactions were reviewed by Lindquist and colleagues.
In line with this, the more distal sperm head area, where the membrane interaction was not observed (Fig. 1C), did not show the stripping of the OAM (Fig. 2C).
The mechanism of membrane interaction is poorly understood.
Neither of the two fragments induced membrane tubulation emphasizing that membrane interaction is indeed required for this phenotype.
Our data also suggest that the N-terminal membrane interaction is mediated via a pair of basic amino acids.
Related(20)
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