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Since RbbA and YhjD share these common motifs, we performed reciprocal affinity purification in the presence of three detergents using an endogenously expressed SPA-tagged YhjD strain and searched for physical interactions with other E. coli proteins and membrane functions as well its possible functional connection with RbbA in protein synthesis.
A protein channel embedded in a cell membrane functions as a natural regulator in the biological system.
The protein complex, Pxa1p-Pxa2p, which embeds in the peroxisomal membrane, functions as transporter and translocates activated fatty acids into peroxisomes for beta-oxidation, utilizing the energy of ATP hydrolysis.
The cell membrane functions as a selective filter, allowing molecules either to be pumped across the membrane by transmembrane transporters, or to be diffused through protein channels.
Hence, there is a possibility that the cytochrome c accumulated in large amounts on the outer surface of membrane functions as an electron and H+ condenser.
The cardiac ryanodine receptor (RyR2) located in the sarcoplasmic reticulum (SR) membrane functions as a Ca2+ release channel through which, on Ca2+-induced Ca2+ release, Ca2+ flows from the lumen of the SR into the cytoplasm and activates cardiomyocyte contraction.
Similar(53)
Loss of RBC membrane function, as well as an increased tendency to adhere to endothelium, may interfere with microcirculatory flow [ 72, 73].
The observation that 16-C fatty acids show a pattern distinct from that of 18-C fatty acids suggests that individual fatty acid classes may have specific roles in maintaining optimal membrane function as well as different mechanisms governing their synthesis.
LCn-3PUFA supplementation in conjunction with standard pharmacotherapy may lead to additive improvements in membrane function, as lithium and valproate treatment is associated with decreased AA turnover without altering DHA turnover (Chang et al., 2001).
This labeled nanofibrous membrane function as a novel radio-medical appliance with excellent surface hydrophilic and mechanical properties that can be directly implanted into the lesions not only to locally kill the cancerous cells but also to play the anti-adhesion role at where surgical procedures have been made to remove the tumor tissue.
It has been suggested that the tolerance of Gram-negative bacteria to antibacterial substances is related to the hydrophilic surface of their outer membrane, functioning as a barrier to the penetration of various molecules, and is also associated with the enzymes in the periplasmic space, which are capable of breaking down the molecules [ 37, 38].
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