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Exact(6)

The state of the current understanding of membrane fission is less advanced.

Vps1 can also function in peroxisomal fission indicating that its ability to drive membrane fission is relatively promiscuous.

We will likely discover many more examples as the importance of hydrophobic insertions in membrane fission is recognized.

Furthermore, the observation that the separated membranes before degradation were converted to continuous membranes after degradation suggests that membrane fission is reversible during DNA translocation and depends on the integrity of the paired channel.

Our results demonstrate that SpoIIIE is required in both cells to maintain separate septal membranes during DNA translocation and that septal membrane fission is reversible in the presence of trapped DNA.

In addition to the data presented here, the paired channel model for septal membrane fission is supported by our previous demonstration that septal membrane fission depends on the SpoIIIE transmembrane domain (Sharp and Pogliano, 2003) and its large extracellular loop (Liu et al., 2006) and on the assembly of a compact focus (Fleming et al., 2010).

Similar(54)

The emergence of aberrant TfnR-positive tubules that appear resistant to fission suggests that endosomal membrane fission machinery is dysfunctional in ATP8A1-depleted cells.

The envelope membrane fission event is performed by ring structures at the division site, encompassing both the inside and the outside of the two envelopes.

Moreover, the essence of the described effect of hydrophobic insertions on the membrane elastic properties relevant for fission is generation of negative values of the modulus of Gaussian curvature κ ¯ B of the neck membrane.

Specifically, at large values of ϕ, where the values of the Gaussian modulus can be considerably more negative than the used number, membrane fission will be even more favorable than that predicted by the phase diagrams below.

Fission is mediated by outer membrane Fis1 and Mff, which recruit Drp1 as the molecular motor of fission.

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