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Expression of many KLF family members were enriched in ES cells and rapidly down regulated upon differentiation.
PD-Quest analysis showed that both prohibitin family members were enriched in DIMs with respect to P2 (Fig. 5Ba,b; supplementary material Fig. S2 and Fig. S4C).
As described previously, we identified only a small subset of regions in the mouse genome where MSL complex members were enriched exclusively (see cluster E in Figure 2).
We exemplified such analyses by looking at three microRNA modules whose target gene members were enriched in KEGG pathways: miR-30a, miR-16 and let-7e modules.
Though the NF-Y family members were enriched in the 2nd cluster, the binding site of NF-Y was not obviously enriched in any clusters using different length of putative promoter sequence.
Similar(55)
10.7554/eLife.02024.013 Figure 4. MSL and NSL complex members are enriched at regions with enhancer marks in ESCs.
Such setting allows brainstorming and sharing processes; the group members are enriched by the mutual exchange of each member's perspective and experience.
We found that motifs for ETS and Runt family members are enriched in the GM12878-specific, distal, non-Kaiso motif set.
First, they tend to identify pathways with broad functions such as proliferation and apoptosis, whose gene members are enriched in the genes with dosage effect.
Interestingly, in addition to c-Fos and c-Jun, many AP-1 family members are enriched in the activated enhancer clusters as well, namely fra-1 (FOSL1), jun-B (JUNB), jun-D (JUND), and B-ATF (BATF).
3. Two distinct classes of enhancers associated with activated or repressed chromatin, are significantly enriched for binding sites of two different sets of TFs. 4. The upstream pathways and downstream targets of the TFs linked to activated enhancers (AP-1 and NF-κB family members) are enriched for genes with EMT-specific epigenetic profiles.
Related(20)
members were acquired
members were enhanced
members were energized
members were facilitated
members were increased
members were improved
members were strengthened
members were persuaded
members were charged
members were injured
members were stumped
members were proposed
members were fired
members were sounded
members were consulted
members were outraged
members were blunter
members were urged
members were given
members were thrown
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