Sentence examples for mediators of many from inspiring English sources

They particularly influence extracellular matrix (ECM) gene expression, ECM protein synthesis, and production of inflammatory mediators of many load‐sensitive adult cells such as fibroblasts, chondrocytes, smooth muscle cells, and endothelial cells.

Hedgehog (Hh) family of intercellular signalling proteins are one of the key mediators of many fundamental processes in embryonic development, and are particularly essential to the development of nervous system in gnathostomes (reviewed in [9], [10]).

MiRNAs are essential mediators of many biological processes.

Receptor tyrosine kinases (RTKs) are primary mediators of many of these signals and thus determine the fate of the cell: growth, differentiation, migration, or death.

Given that T cells are considered important cellular mediators of many arthritic diseases, one may reason that their aberrant autoreactive responses also contribute to coincident uveitis.

Biologically active leukotrienes are mediators of many pro-inflammatory and allergic reactions, therefore the inhibition of the synthesis of leukotrienes by 15-LOX is considered as one of the therapeutic strategies in the management of inflammatory conditions [ 17, 24].

Literature published in past few years increasingly suggests that H2S is a mediator of many physiological and/or pathological processes.

CRF is the molecular mediator of many of these effects of stress on drug taking behavior [67].

Nitric oxide (NO) is a molecular mediator of many physiological processes, including mechanisms that contribute to neurological disorders such as Alzheimer's disease and PD [31].

In fact, JNK signalling appears to be a central mediator of many of the cell-autonomous phenotypes observed in dVps4-deficient cells.

Autophagy is an important mediator of many pathological responses.