Sentence examples for mediating focal adhesion from inspiring English sources

Pathways mediating focal adhesion, integrin-mediated cell adhesion, G13 and TOR signaling are used in several biological processes including cell motility and proliferation, cell differentiation and gene expression or cell survival and cell cycle regulation, often linking extracellular signals with other intracellular signaling pathways.

It also has counter-adhesive properties, inducing cell rounding, inhibiting cell spreading [2], and mediating focal adhesion disassembly and reorganization of actin stress fibers [3].

EPM has the ability to guide MO determination of WB-F344 cells along the tangential direction of a cell-EPM contact surface via mediating focal adhesion assembly and F-actin bundle alignment, which may be vital to the bile duct-like formation of WB-F344 cells.

However, another gene mediating focal adhesion, MYLK, was downregulated in tumor cells.

Importantly, it is becoming increasingly recognized that microtubules also play an important role in governing the mechanical properties of the cell as they play a role in generating traction forces and mediating focal adhesion dynamics.

Traction stress exerted by cells on the extracellular matrix mediates focal adhesion stabilization and regulation of the cytoskeleton for directing biological activity.

It has been shown that syndecan-1 can colocalize with α2β1 integrin and support integrin-mediated adhesion to collagen [31], [39] and syndecan-4 can cooperate with α5β1 integrin and mediate focal adhesion formation on fibronectin [54].

Microtubule-mediated focal adhesion (FA) disassembly is a clathrin- and dynamin-dependent process.

The transmembrane glycoprotein neuropilin 1 forms a complex with VEGFR2 and acts as a co-receptor to enhance VEGF-A binding, mediate focal adhesion kinase phosphorylation and increase cell migration (Herzog et al., 2011).

FER was shown to play a key role in the coordinate regulation of E-cadherin-mediated cell-cell adhesion and integrin-mediated focal adhesion.

Cell mechanosensing is mediated by focal adhesion contacts [ 66].