Sentence examples for mediated by pathogenic from inspiring English sources

Ventricular remodeling is a complex process mediated by pathogenic factors all of which interact at the cellular, ventricular and systemic levels to cause progressive left ventricular dilation and subsequently a heart failure syndrome.

The breakdown of tolerance to β-cells is the cause of T1D, an autoimmune disease mediated by pathogenic T cells.

Functional synaptic deficits mediated by pathogenic Aß in vulnerable pathways may provide a means of developing much-needed therapeutic avenues [ 2].

This IgG-depleting mechanism plausibly explains the beneficial results of intravenous therapy with high doses of normal IgG (IVIG) in autoimmune diseases mediated by pathogenic IgG.

In addition to this, CIA is mediated by pathogenic B cells, which produce anti-collagen antibodies that are indicative of disease development [ 5] and can induce arthritis upon transfer [ 6, 7].

The innate immune response is the first line of pathogenic defense which can be mediated by pathogen-derived signals such as lipopolysaccharide (LPS) from gram negative bacteria or viral DNA which are recognized by toll-like receptors (TLRs).

Thus, the altered trafficking of mCAT1 appears to be an active process mediated by live pathogenic bacteria and is independent of LPS.

In support of this hypothesis, infection of WSX-1-/ mice with T. gondii leads to acute mortality mediated by a pathogenic accumulation of activated Th1 cells (Fig. 3) [ 21].

This indicates that fixation of genes in the human genome coding for ITAM-bearing CEACAMs can be the result of a selective pressure mediated by CEACAM-binding pathogenic microbes.

These data indicate that protective effect of WA in AD progression is mediated by down-regulation of pathogenic chemokines and cytokines in the inflamed tissues, resulting in significant reduction of infiltrated pathogenic immune cells.

These results suggest that ameliorated AD symptoms by GCSE treatment is mediated by down-regulation of pathogenic cytokines.