Sentence examples for mediated by Fc-mediated from inspiring English sources

Secondly, anti-tumor effects are mediated by Fc-mediated ADCC.

Taken together, we have shown that the use of mIgG in animals receiving AngII can enhance the primary inflammatory reaction within the myocardium and this appears to be mediated by Fc-mediated activation of monocyte-derived cells.

Karsten et al. (2012) recently reported an anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIb and dectin-1.

This indicated that increased cholesteryl ester uptake was likely mediated by receptor-mediated endocytosis.

Calcidiol uptake is mediated by megalin-mediated endocytosis of the VD binding protein calcidiol complex.

The anti-adhesive property by insulin may be mediated by the Akt-mediated and NO-dependent pathway.

Intracellular uptake of HA-ss-PTX toward MCF-7 cells was mediated by CD44-caveolae-mediated endocytosis.

Thus, the primary mode of action of TNF inhibitors in RA does not appear to involve Fc-mediated effects but rather the binding and inactivation of TNF and, probably, reverse signalling, 35 36 which can also be mediated by an Fc-free Fab′ molecule such as certolizumab pegol.

The electron transfer was further enhanced by using multiwalled carbon nanotubes (MWCNTs) and mediated by ferrocene (Fc) entrapped in the cryogel pores wall.

Additionally, it was shown that antibody therapeutics can lead to increased inflammatory responses mediated by the Fc domain of full IgG antibodies.

This was mediated by macrophage Fc receptors [ 2], and occurred without destruction of the lymphocyte.