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Exact(5)
Similarly, glycosylation of AIDA-I is required for normal conformation and for AIDA-I mediated adhesion to epithelial cells [39].
In agreement with published findings active R-Ras increased cell adhesion [16]; however we detected no difference in R-Ras mediated adhesion to FN in FLNaΔ3 or FLNa- expressing cells (Fig. 3C).
Interestingly, integrin mediated adhesion to the ECM was shown to negatively regulate terminal differentiation of cultured keratinocytes in vitro, while ectopic expression of β1 integrins in suprabasal cells leads to epidermal hyper-proliferation and perturbed keratinocyte differentiation in vivo [13], [14].
We used a panel of anti-integrin antibodies to determine which integrins mediated adhesion to SPRGDVC and KKKDLFEIFEIERC.
An alternative possibility is that maspin, through an unknown mechanism, prevents invasion by increasing the strength of integrin mediated adhesion to the ECM.
Similar(54)
PSGL-1-mediated adhesion to selectin on endothelial cells mediates rolling and capture of neutrophils [1], [2].
In fibroblasts it regulates integrin-mediated adhesion to the extracellular matrix.
The growth and survival of many cell types requires integrin-mediated adhesion to the extracellular matrix (ECM).
These factors exerted their effects through dynamic fine regulation of integrin-mediated adhesion to the ECM.
Als-mediated adhesion to substrate is followed 5 20 min later by aggregation of Als-expressing yeast cells [20].
It has been shown that syndecan-1 can colocalize with α2β1 integrin and support integrin-mediated adhesion to collagen [31], [39] and syndecan-4 can cooperate with α5β1 integrin and mediate focal adhesion formation on fibronectin [54].
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