Sentence examples for mediated a reduction from inspiring English sources

In the present investigation tocotrienols mediated a reduction of LDL-C from an average of 179 mg/dl to 104 mg/dl.

Gene-modified T cells survived, expanded and mediated a reduction in HBsAg levels without exacerbation of liver inflammation or other toxicity.

Even more importantly, when administered orally to PiZ mice the drug mediated a reduction in hepatic ATZ load and in hepatic fibrosis (Hidvegi et al., 2010).

More importantly, CBZ mediated a reduction on hepatic ATZ load and ameliorated hepatic fibrosis in the PiZ mouse model of ATD [ 6].

We started by analysing the role of PI3K activity as a VPA target, because our previous work had shown that both VPA treatment and pharmacological inhibition of PI3K activity (using LY294006) (Xu et al., 2007) mediated a reduction in Dictyostelium phosphoinositide levels and a reduction of glutamate release in isolated rat hippocampal cells.

America is trying to mediate a reduction in tensions, and Israel last Friday removed all age restrictions for Muslim worshippers.

Potential molecular targets include the protein kinase A and C phosphorylation sites on troponin I, which, when phosphorylated, mediate a reduction in calcium sensitivity and a reduction in maximal actomyosin adenosinetriphosphatase activity, respectively.

In addition, SOCS3 has been shown to mediate a reduction of β-cell volume and modulates cytokine signalling in pancreatic β-cells [2].

Finally, we hope that this study gives us new insights into acquired ciliopathies due to the effects of cigarette smoke and improves our understanding of the biologic processes underlying airway epithelial cilia growth, and the mechanisms of how cigarette smoke mediates a reduction in cilia length.

To our knowledge, this is the first report that an intervention strategy that reduces empiric antibiotic duration may mediate a reduction in risk-adjusted mortality.

Furthermore, a defect in incretin-induced stimulus secretion coupling could mediate a reduction of insulin secretion in carriers of the TCF7L2 polymorphisms.