Sentence examples for mediate firm adhesion from inspiring English sources

Separately, sLeX/P-selectin interactions support rolling and aICAM-1/ICAM-1 interactions mediate firm adhesion.

This interaction would mediate firm adhesion of the leukocyte to the endothelium, aiding the inflammatory response post surgery.

After injury ICAM-1 interacts with leukocyte integrins to mediate firm adhesion of activated neutrophils to endothelium and diapedesis [ 4– 7].

The capacity of p85β to enlarge the number of centrally localized larger cell adhesions concurs with p85β enhancement of cell adhesion, as centrally localized adhesions mediate firm adhesion (Wolfenson et al., 2013).

Arrest chemokines, such as CXCL2, CXCL8, and CCL5 (alone or as heterodimer with CXCL4) bind to the glycosaminoglycans on the surface of endothelial cells, immobilize, and mediate firm adhesion of rolling monocytes.

The initial steps of the leukocyte adhesion cascade include capture and rolling of circulating leukocytes and require E-, L- and P-selectin [ 27], whereas integrins – heterodimeric transmembrane glycoproteins – mediate firm adhesion by interacting with intercellular adhesion molecules (e.g. intercellular adhesion molecule [ICAM]-1, ICAM-2, vascular cell adhesion moleculre [VCAM]-1) [ 28].

In particular, VCAM-1 mediates firm adhesion, tethering, rolling of monocytes and facilitates their transendothelial migration at the developing atheroma [26].

ICAM-1 is an important surface receptor in the immunoglobulin family, which mediates firm adhesion of monocytes to endothelium.

The αMβ2 (Mac-1) integrin mediates firm adhesion of leukocytes to inflamed vessels by interacting with its endothelial cell counter-receptor intercellular adhesion molecule-1.

Intercellular adhesion molecule-1 (ICAM-1), a cell surface molecule of the immunoglobulin superfamily, mediates firm adhesion of circulating neutrophils and thereby enhances their transmigration through the endothelial barrier.

Indeed, leukocyte adhesion during inflammation is thought to proceed in a cascade-like fashion, in which selectins are responsible for leukocyte capture and rolling, and integrins for mediating firm adhesion and transmigration [ 5, 6].