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To evaluate the subjective and objective measures of ocular surface disease in patients with glaucoma.
Previously used and accepted scalar measures of ocular dominance were then used to quantify the single-unit distributions in each hemisphere [8], [9].
As shown in Fig. S3A D, while TRA has clear effects on the sleep/wake architecture of these cats, it does not change scalar measures of ocular dominance.
This inhibition was evident in the ocular dominance distribution of neurons recorded from TRA-treated cats (Fig. 3A), and also from scalar measures of ocular dominance (Fig. 3B).
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Similar trends were observed using intrinsic signal imaging as a second measure of ocular dominance plasticity (with lower overall values in the TRA group; Text S1, Fig. S2), but these did reach significance when the VEH- and hypnotic-treated groups were compared directly (one-way ANOVA, N.S).
However, according to Robboy et al. sighting dominance alone is not an adequate measure of ocular dominance [ 18].
Corneal pachymetry has been shown to be a predictive measure of ocular irritation resulting in edema in the corneal epithelium [ 24].
As demonstrated by the low OSDI scores (the gold standard measure of ocular surface damage [ 34]), both bim/tim and dorz/brim/tim had minimal, if any, detrimental effects on the ocular surface.
In this study, differential gene expression analysis with Affymetrix gene arrays showed that antagonism of the LTBR-axis altered the expression of a wide variety of genes related to lymphocyte trafficking, lymphocyte function and lacrimal gland function, and these changes coincided with improvement in tear fluid secretion and ocular integrity, two measures of overall ocular health.
Limitations are inherent in any pooled analysis, though the two studies pooled in the present analysis demonstrated consistent findings across measures evaluating relief of ocular itching.
Opinions about tests were less certain but most included a measure of intra ocular pressure.
Related(18)
measures of visual
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