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Exact(5)
Even if just recording the incidence of AEs in the balance between efficacy and tolerability is not the ideal measure of tolerability it is fair measure for the potential for AEs of a triptan in the migraine population and in several cases the incidence of AEs has determined the recommended doses of the triptans.
The discontinuation rate due to adverse events was a measure of tolerability.
Dropout rates for the active versus control group were chosen as a measure of tolerability.
The primary endpoint was a measure of tolerability, and the study included a prospective, real-time evaluation of changes of pre-specified cardiovascular biomarkers over 96 weeks.
The use of multiple grade 2 toxicities in the determination of the MTD was considered to be a practical approach and one that provided a realistic measure of tolerability.
Similar(55)
Side effects discontinuation as a measure of treatment tolerability is defined as the proportion of patients who drop out for any reason.
For gastrointestinal adverse events, we included an overall measure of gastrointestinal tolerability as well as individual gastrointestinal adverse events of nausea, vomiting, abdominal pain, dyspepsia, diarrhoea, and ulcers or bleeds.
Secondary objectives were to assess further measures of efficacy, tolerability, and safety.
The secondary objectives were to compare further measures of efficacy, tolerability, and safety of 2 weeks of treatment with bibrocathol ointment versus vehicle.
This core Case Report Form battery consisted of basic patient, practice, and diagnostic information for screening and enrollment, along with a standard treatment-level form that included validated and reliable measures of safety, tolerability, and efficacy.
In equivalence (or non-inferiority) trials, the active control is usually an established antiepileptic drug (AED) such as carbamazepine or valproate, and outcome parameters may include proportion of patients achieving a predefined (for example, 6-month) seizure remission or the proportion of patients remaining in the trial (retention rate, a combined measure of efficacy and tolerability).
Related(19)
measure of error
rating of tolerability
measure of intolerance
measure of sustainability
measure of toleration
measure of reflectivity
measure of factory
measure of engine
measure of vulnerability
measure of success
measure of time
measure of love
measure of wealth
measure of freedom
measure of truth
measure of greatness
measure of comfort
measure of anxiety
measure of tolerance
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