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Their effectiveness in terms of crime prevention is both context and time dependent, and for this reason it is normally assessed when they are implemented in a given ecosystem by means of randomised control trials or quasi-experiments (Pawson and Tilley 1997).

Traditional systematic reviews such as those undertaken with the Cochrane Collaboration, generally privilege evidence gathered by means of randomised control trials.

assess the impact of implementation of the assay on clinical outcomes by means of randomised controlled trials (one such trial is in progress: http://clinicaltrials.gov/show/NCT01770730; vii. assess cost-effectiveness in different settings and algorithms. viii.

12 When these issues can be controlled, retrospective studies may however provide valuable information that is impossible to access by means of randomised prospective studies of selected patient materials.

As raised tHcy can be lowered with B-vitamin therapy, [ 15, 16] it is possible to determine whether tHcy is a causal risk factor for bone fracture by means of randomised controlled trials (RCTs) of B-vitamins vs. placebo.

Similar(55)

Design: Systematic review and meta-analysis of randomised, controlled trials.

Design: Systematic review with meta-analysis of randomised or controlled trials.

"A lot of games feature small elements of randomised music.

A more detailed assessment of risk of bias is included in Additional file 2. The mean number of patients randomised was 70 (range 37 120).

The mean number of patients randomised was 63 (range 32 101).

The current study was designed to address these methodological issues by means of a single-blinded, randomised, controlled cross-over trial of high strength, certified pure lavender oil with proven neurophysiological activity.

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